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Back Issues  —  1998

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1998 NEWS ARTICLES
Abacavir recommended for approval for use in AIDS combination therapy December 1998:New study data suggest that abacavir sulfate may have greater antiviral activity than other available nucleosides.
ACIP considers use of Lyme vaccine August 1998: Two Lyme disease vaccine license applications are currently under review by the FDA.
Adding nasal steroid to therapy may improve sinusitis symptoms faster November 1998: Is a shorter course of therapy better than a traditional one in treating sinusitis in AIDS patients?
AIDS epidemic traced back to 1959 March 1998: HIV-1 sequence from 1959 has important implications for the origin of the epidemic.
AIDS vaccine development: how much farther science has to go May 1998: Several "targets" have been sighted, but some doctors say an AIDS vaccine is still years away.
Alopecia linked to HepB immunizations, in rare cases April 1998:ACIP voted to add this adverse event to the hepatitis B recommendation statement.
Anabolic steroids in HIV/AIDS wasting syndrome November 1998: The concurrent use of an appetite stimulant, anabolic agent and resistance exercise should increase caloric intake and promote the production of lean body mass.
Another interesting year for infectious diseases December 1998
Antibiotic control methods help to lower resistance August 1998: Monitoring antimicrobial use and educating both practitioners and patients may enhance susceptibility.
Antibiotics widely used in agribusiness January 1998: Judicious use of antibiotics is going to have to include controls in animals and other food products.
Are isolation precautions necessary to prevent transmission of multidrug-resistant organisms? August 1998: Health care institutions have two major responses to halt resistance: promote judicious use of antibiotics and encourage infection control to prevent nosocomial transmission of resistant organisms. There is little controversy about the first approach. However, there is less agreement about the second. Two infection control experts argue the point here.
Bacteria cocktail fights Salmonella in chickens April 1998: The Food and Drug Administration approves the use of Preempt spray to combat Salmonella and other microbes infecting chickens.
CDC data show increase in reported pertussis cases December 1998: Increased awareness is placing pertussis in the differential for chronic cough.
CDC expands strategy for refugee medical screening September 1998: Approximately 100,000 refugees resettle in the United States each year.
CDC plans next phase to combat emerging infections November 1998: The full implementation of the updated plan will cost an estimated $200 million annually.
Cesareans with AZT could cut HIV infection in at-risk infants August 1998: Findings give hope that HIV-infected mothers can avoid transmitting virus to their unborn children.
Certain immune activity may control HIV levels January 1998: Finding may explain how a few people are able to avoid developing AIDS.
CFS patients may benefit from steroids, but with risky effects December 1998: Steroids offer some symptomatic improvement, but not enough to justify the risk of adrenal suppression.
Change in diets of cattle might control E. coli October 1998: Acid-resistant E. coli 0157:H7 bacteria that survive human stomach acid are coming from grain-fed cattle.
Clusters of cyclosporiasis cases reported in Canada December 1998: This represents the third consecutive year in which raw produce has caused cyclosporiasis outbreaks.
Combination therapy for children with AIDS becoming treatment standard March 1998: Once thought to be inappropriate for children, these therapies have proven highly effective.
Cryptosporidiosis outbreak linked to Minnesota Zoo water fountain May 1998: Physicians should be aware of what their labs are checking for when they send stool samples for analysis.
Cryptosporidiosis poses serious risks for patients with HIV February 1998: Cryptosporidium parvum's high infectivity puts a premium on prevention in the immunocompromised.
Data show nasal influenza vaccine effective December 1998: Protection provided against the predominate influenza strain during last year's flu season.
Death of Pennsylvania man linked to HantavirusDisease January 1998: First victim to die of Hantavirus pulmonary syndrome in Pennsylvania.
DNA vaccine proves effective against rabies in monkeys September 1998: Six months after challenge with lethal doses of the virus, all vaccinated primates showed no signs of disease.
Doctor infected with HIV through needlestick wins $12 million lawsuit February 1998: "Dr. Jane Doe" contracted the virus during her first year as an intern at Yale School of Medicine.
E. coli outbreaks in Chicago and Georgia: largest in history July 1998: Local health officials stunned over the large number of infected people flooding into hospitals.
Eight genetic groups of wild-type measles identified; more are expected February 1998: Group three viruses have recently become the predominant genotype.
Extreme hydrologic events may cause waterborne disease outbreaks August 1998: Studies show that outbreaks are often preceded by heavy precipitation and climate change.
Famciclovir effective in surpressing herpes October 1998: Patients taking a 250 mg once-daily dose of famciclovir experienced fewer recurrences per year than placebo.
FDA advisory committee recommends Synercid for approval March 1998: If approved, Synercid would represent the first new class of antibiotics in nearly 25 years.
FDA advisory panel recommends influenza virus vaccine strains March 1998: One strain of the trivalent vaccine was recommended; the second and third strains will be chosen pending further data.
FDA advisory panel rejects application for Cryptaz July 1998: The panel felt that current HAART drugs were effectively helping to eradicate Cryptosporidium infection in AIDS patients.
FDA approves new human rabies vaccine February 1998
FDA/CBER budget cuts may impact funding for vaccine research December 1998: Reauthorization of the vaccine user-fee act states that user fees can no longer support vaccine research.
FDA panel reviews cholera vaccine; does not recommend approval August 1998: The proposed indication of the vaccine is for individuals 2 years and older
FDA panel recommends approval of vaccine for rotavirus infection January 1998: RotaShield has proven 100% effective in preventing dehydration from rotavirus-induced diarrhea.
FDA panel rejects the idea of adding a boxed warning label for OPV July 1998: Not the best way to inform physicians and parents about the risk, panel says.
FDA panel reviews cholera vaccine; does not recommend approval July 1998: The proposed indication is for individuals 2 years and older who are traveling to cholera-endemic areas; not for routine administration.
Fixing the black eye given to pneumococcal vaccination April 1998:A lesson from the Swedish study is that attempts to increase pneumococcal vaccine use no longer require randomized, controlled trials to prove efficacy.
Flu vaccine chosen for Southern Hemisphere November 1998:
Four deaths and fourteen cases of avian flu confirmed in Hong Kong January 1998: Chinese health officials identify cluster of rare influenza;concerns raised about potential pandemic.
Frozen remains of 1918 influenza victim located in Alaskan village March 1998: Researchers are at work decoding genetic material of the strain that killed 21 million people worldwide.
Gastrointestinal illness appears to be increasing April 1998: Changes in diet, food production and population seen as reasons for the increase.
Gene therapy holds promise as possible treatment for AIDS September 1998: Studies of twins reveal that genetically altered immune cells can suppress HIV replication.
Global HIV rates continue to climb, according to UN report July 1998: Although some developing countries have recorded drops in HIV infection, many more have been unsuccessful.
Global warming could foster spread of dengue fever April 1998: Most of the areas at increased risk are temperate regions that border endemic areas.
Health problems of Vietnam veterans may be due to cerebral malaria February 1998: As many as 250,000 Vietnam veterans may have contracted cerebral malaria.
Herpesvirus identified as a possible MS trigger January 1998: Recent study adds evidence to the role of viral triggers in multiple sclerosis.
High mortality rate observed in cholera outbreak September 1998: Case-fatality ratios of 1% or less are expected if rehydration services are available.
High prevalence of chlamydia and gonorrhea found in Baltimore students April 1998: Study found that most of the infected students were asymptomatic.
HIV and tropical diseases form deadly alliance February 1998: Research indicates that tropical diseases accelerate the spread of the HIV in many parts of the world.
HIV cluster outbreak in an upstate New York county linked to felon January 1998: About 1,383 people have been tested, 14 people have tested positive.
ID physicians, ED staff are first line of defense against biological terrorism July 1998: Survival of health care personnel may be at stake because they could become infected before they realize their patients are highly contagious.
Increased spending on TB programs one reason for drop in U.S. rates May 1998: Tuberculosis, once thought under control, is now the number one infectious killer worldwide.
Influenza A(H5N1) widespread in Hong Kong market March 1998: The slaughter of 2 million chickens in January may have prevented an influenza pandemic, experts say.
Influenza mortality, morbidity rates change after pandemic October 1998: Death rates among those younger than 65 are higher during a pandemic than in the decade following.
Is tuberculosis hiding in your health care facility? December 1998: Medical facilities may not be told if health care workers have a reactivation of tuberculosis.
Latent virus pools in CD4 T cells pose danger to immune system March 1998: Reservoirs of resting memory T cells continue to pose dangers to host's immune system even after drug treatment.
Latex allergies can pose significant health risk May 1998: Most latex glove allergies aren't to the latex itself, but to the chemicals used to make the latex.
Lifelong immunization records developed by Oregon Health Division. October 1998: A durable, wallet-size immunization record is useful for health care providers, school staff and parents.
Lyme disease is overdiagnosed and treated too often, study says April 1998: Aggressive medical treatment may not be needed for those suffering from the tickborne infection.
Malaria transmission on the rise again in U.S. February 1998: Increased antibiotic resistance, air travel, and changes in the environment cited as causes.
Mass treatment for curable sexually transmitted diseases has mixed results August 1998: Study finds some STD rates have fallen, but HIV incidence remains unchanged.
Mother who refused treatment for HIV-infected son wins in court. October 1998: Maine case could have repercussions for pediatric AIDS treatment for the rest of the country.
Mycobacteria and the association with antiretroviral therapies November 1998: Antiretroviral therapy may precipitate symptomatic infection due to dormant Mycobacteria
Name-registration of HIV patients on the table in several states July 1998: List of names could have implications on testing and treatment of patients.
New data from zinc lozenge study questions efficacy against common cold August 1998
New drug may reduce duration and severity of influenza symptoms October 1998: In clinical studies, zanamivir reduced the risk of influenza illness by 67% and decreased the duration of the illness.
New FDA proposals intended to increase safety of fresh juices May 1998: The FDA estimates between 16,000 and 48,000 cases of juice-related illnesses occur each year.
New quinolone receives marketing clearance January 1998: The approval comes after testing in more than 13,000 people.
New strain of HIV discovered in Africa September 1998: French researchers obtained an isolate from a woman who contracted AIDS from an unknown source.
No difference seen in cardiac conditions of Lyme disease sufferers May 1998: Patients with history of Lyme disease did not have higher prevalence of cardiac irregularities.
Non-traditional sites could increase adult immunization rates March 1998: Many barriers must be crossed before these programs can be efficiently and effectively put into place.
Outbreak of Campylobacter reported in Oklahoma April 1998: Poultry was not separated from fresh vegetables during preparation.
Overuse of Triclosan may be creating resistant bacteria September 1998: Repeated use of the bacteria fighter could cause resistant strains to emerge.
Patients on HAART can still transmit HIV, must continue practicing safe sex December 1998: Although HAART may lower viral loads to undetectable levels, genital secretions may be reservoirs for latent HIV.
Permission needed to study Cuban-made vaccine September 1998: The vaccine might prevent the 1,000-2,000 U.S. cases of meningococcal type B meningitis each year.
Person-to-person Hantavirus suspected in Chile November 1998: A cluster outbreak of Andes virus within a six-month period yields person-to-person transmission.
Pfiesteria piscicida studies underway in six states May 1998: More than $3 million was distributed among six states to conduct studies of this mysterious organism first discovered in 1991.
Pharmaceutical industry urges FDA to classify bacteremia as a disease. October 1998: Defining bacteremia as a primary infection would allow the industry to focus on developing specific antibiotics.
Physicians seeing resistance to protease inhibitors transmitted September 1998: Researchers from San Francisco report one transmitted protease-resistant strain, while Swiss doctors have detected several resistant strains.
President Clinton announces initiative to improve juice safety August 1998: Clinton plans to create a Joint Institute for Food Safety Research to develop a coordinated food safety strategy.
Primate virus kills researcher January 1998: The herpes B virus, common among macaque monkeys, is fatal in 70% of humans who contract the disease.
Proper storage of vaccines is needed to maintain effectiveness September 1998: Appropriate storage and handling of vaccines is necessary to ensure adequate protection.
Proper treatment of diabetic foot ulcers can prevent amputation May 1998: Aggressive débridement is the first, and most important, step in healing neuropathic ulcers.
Research reveals why bone loss occurs during steroid treatment August 1998: Unlike common age- and gender-related types of osteoporosis, steroid-induced bone loss occurs at any age.
Resistant strain of Salmonella causes outbreak in Vermont May 1998: The outbreak of Salmonella typhimurium DT104 in Vermont is the first such occurrence in the U.S.
Resistant TB spreads among 18 high school students February 1998: Source patient was found to be infectious for more than two years before he was diagnosed.
Research looks at PML patients without treatment November 1998: AIDS therapists try to determine clinical benefit of HAART in patients coinfected with PML disease.
R.I. health officials recommend routine use of meningitis vaccine April 1998: Since Jan. 1, a total of 11 cases have been reported, and three children have died.
Rubella outbreak in New York spreads to surrounding area March 1998: The outbreak is affecting young Latino men who are susceptible to disease.
Salmonella outbreak in 11 states caused by tainted oat cereal July 1998: Over 200 cases of Salmonella agona infection reported; 47 people hospitalized.
Scientists decipher key AIDS glycoprotein July 1998: This piece of the virus's puzzle could be used to design a workable vaccine.
Short-course of AZT effective in reducing perinatal HIV transmission March 1998: New regimen offers hope for reducing mother-to-child HIV transmission in the developing world.
Some AIDS therapies cause unusual fat deposits April 1998:Studies indicate side effects of therapies can include disfiguring humps on shoulders and back and a "protease paunch" around mid-section.
Staph, strep most common waterborne infections May 1998: Following Staphylococcus and Streptococcus Mycobacterium marinum is the most common aquatic infection seen in children.
State and local flu preparedness plans are nearing completion October 1998: The CDC hopes that eventually each state will have its own influenza pandemic preparedness plan that coordinates with the federal plan.
Stopping PCP prophylaxis an option for AIDS patients improving on HAART November 1998: Should clinically improving AIDS patients threatened with opportunistic infections be taken off PCP therapy?
Study indicates influenza drug shortens recovery time November 1998: Drug for the treatment and prevention of influenza being developed; scheduled for FDA review within the next year.
Study says targeted Lyme disease vaccination is best August 1998
Summer outbreaks of influenza A reported in Florida and Tennessee November 1998: The outbreaks, reported in July and August, continue a trend of increased influenza activity during the summer.
Survey indicates doctors are missing opportunities to detect HIV in women November 1998: The number of women contracting HIV is increasing, making proper diagnosis all the more important.
Testosterone may lessen depression in AIDS patients November 1998: Studies at the New York State Psychiatry Institute find steroid injections helpful against HIV fatigue in patients.
Thalidomide approved for use in leprosy patients August 1998: Women using thalidomide will be required to undergo a monthly pregnancy test to avoid fetal exposure.
The hidden plague: Number of AIDS orphans rising February 1998
Toxin affects waterways along eastern Chesapeake estuaries September 1998: Fishermen complain of symptoms after being exposed to water contaminated with Pfiesteria piscicida
Two-thirds of U.S. population infected with herpes simplex 1 October 1998: Infection is slightly more common among women than men, and occurs more frequently in some ethnic groups than others.
Unified approach needed for food safety in U.S. October 1998: Experts recommend unifying functions of the FDA and USDA to better protect against foodborne illness.
Unusual strain of Salmonella found in three outbreaks in England September 1998: Salmonella enteritidis phage type 6 responsible for several outbreaks.
U.S. military forces to receive anthrax vaccine January 1998: Associated costs are an estimated $130 million to vaccinate 2.4 million personnel over six years.
Using registries for follow-up of chronic HBV infection October 1998: A study founjd that 20 states have health department registries for patients with hepatitis B virus infection.

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